Test your knowledge of brain metastases in the HER2+ breast cancer setting

In patients with breast cancer, brain metastases are most common among more aggressive disease types, including HER2-positive disease.
True
False
Data from the HER2CLIMB trial in patients with HER2-positive breast cancer with brain metastases led to the FDA approval of which therapy in this patient population?
Stereotactic radiotherapy
Pertuzumab
Trastuzumab deruxtecan
Tucatinib, capecitabine, and trastuzumab
Which of the following radiotherapy options for breast cancer brain metastases is generally well tolerated and has minimal side effects?
Whole-brain radiation
Radiosurgery
Partial-brain radiation
All of the above
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