Clinical Case Series - CLL2 - Question 2

How do you counsel patients with CLL who ask how long they’ll need to continue therapy with ibrutinib?

It’s OK to stop ibrutinib as soon as there is complete remission of CLL and restart again when there is disease progression

At this time, ibrutinib is recommended indefinitely for the best response

If there is complete remission of CLL, you can stop therapy after 5 years

If there is MRD negativity, you can stop therapy after 5 years

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