Test your knowledge on cytopenias after CAR T-cell therapy

Reported rates of prolonged or recurrent cytopenias (grade 3 or higher lasting more than 30 days) can be found in what percentage range of CAR T-cell therapy recipients:

1% to 5%

5% to 15%

20% to 40%

60% to 90%

The only cause of prolonged cytopenias after CAR-T cell therapy is cytokine release syndrome (CRS).

True

False

Management of prolonged cytopenias includes, but is not limited to, which of the following?

Packed red blood cell transfusions

Granulocyte-colony stimulating factor (G-CSF)

Bacterial and fungal infection prophylactic agents

All of the abov

It can be definitively stated that CAR T-cell therapy constructs themselves have no role in the development of prolonged cytopenias.

True

False

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