Test your knowledge of atypical manifestation of neurotoxicity following CAR T-cell therapy

Transverse myelitis can be an atypical manifestation of immune effector cell-associated neurotoxicity syndrome (ICANS).
True
False
Potential treatment for transverse myelitis related to ICANS includes which of the following?
Corticosteroids
Intravenous immunoglobulin
Plasma exchange
All of the above
Moderate to severe ICANS should be treated with which of the following medications?
Tocilizumab
Corticosteroids
Filgrastim
Acetaminophen
Diagnostic evaluation of symptoms related to ICANS should include which of the following?
CT and/or MRI of the brain
EEG
Lumbar puncture
All of the above
Which of the following is a risk factor for developing ICANS?
Female
Younger age
Number of lines of therapy prior to CAR T-cell therapy
History of intrathecal chemotherapy
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