In this case, do you agree with the decision to initiate second-line therapy?
No, I would likely increase steroid again and do a slower taper before considering second line.
Yes, I would have done the same for a patient in my clinic.
My answer is patient-dependent. If they are tolerating steroids well without significant side effects, I would rechallenge. If there were significant side effects, I would go to second line.
I would have hospitalized the patient with the presentation of progression.
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