Test your knowledge on CLL and Richter transformation

An SUVmax of ___ in patients with CLL on a B-cell receptor inhibitor should prompt consideration for biopsy to rule out Richter transformation: 
> 2 
> 5 
> 8 
> 10 
TP53 mutations are associated with increased risk of Richter transformation. 
True
False
Which of these is NOT a potential sign of Richter transformation? 
B symptoms 
Increased lymphadenopathy  
Splenomegaly
Decreased LDH 
Patients with Richter transformation from CLL to Hodgkin lymphoma have improved outcomes compared to those who transform to diffuse large B-cell lymphoma. 
True
False
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