Clinical Case Series - 26aml - Question 1

When NPM1 MRD begins to rise after allogeneic transplant without morphologic relapse, how do you typically approach management in your practice?

Continue observation until morphologic relapse occurs

Increase the frequency of MRD monitoring without initiating therapy

Consider initiating targeted therapy or clinical trial enrollment in the setting of molecular relapse

Proceed directly to second transplant evaluation without additional therapy

Unsure

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